MS Contin (morphine sulfate) dose, indications, adverse ...
For opioid non-tolerant patients, initiate with 15 mg PO every 12 hours (MS Contin), 15 mg PO every 8 or 12 hours (Arymo ER or Morphabond), or 30 mg PO every 24 hours (Avinza or Kadian). With the exception of Avinza, adjust the dose every 1 to 2 days based upon the total daily morphine requirements (extended-release dose plus breakthrough doses). Adjust the dose of Avinza every 3 to 4 days in ...
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